Targeted Genome Modification in Mice Using Zinc-Finger Nucleases

Homologous recombination-based gene targeting using Mus musculus embryonic stem cells has greatly impacted biomedical research. This study presents a powerful new technology for more efficient and less time-consuming gene targeting in mice using embryonic injection of zinc-finger nucleases (ZFNs), w...

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Autori principali: Carbery, Iara D., Ji, Diana, Harrington, Anne, Brown, Victoria, Weinstein, Edward J., Liaw, Lucy, Cui, Xiaoxia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2010
Soggetti:
Investigations
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954478/
https://ncbi.nlm.nih.gov/pubmed/20628038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.117002
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