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Targeted Genome Modification in Mice Using Zinc-Finger Nucleases
Homologous recombination-based gene targeting using Mus musculus embryonic stem cells has greatly impacted biomedical research. This study presents a powerful new technology for more efficient and less time-consuming gene targeting in mice using embryonic injection of zinc-finger nucleases (ZFNs), w...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Genetics Society of America
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2954478/ https://ncbi.nlm.nih.gov/pubmed/20628038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.110.117002 |
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