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Drug-induced anti-histone autoantibodies display two patterns of reactivity with substructures of chromatin.

Increasing evidence suggests that autoantibodies in the rheumatic diseases are a consequence of immune selection by self-material, but the nature of the in vivo immunogen is unknown. Insight into this problem may be obtained by measuring autoantibody binding to various forms of a target antigen. Ant...

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Autors principals: Burlingame, R W, Rubin, R L
Format: Artigo
Idioma:Inglês
Publicat: 1991
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295413/
https://ncbi.nlm.nih.gov/pubmed/1864977
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