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Downregulation of calcitonin receptor mRNA expression by calcitonin during human osteoclast-like cell differentiation.

Calcitonin inhibits both osteoclast formation and bone resorption, and is a primary treatment for patients with hypercalcemia and increased bone turnover. However, the clinical utility of calcitonin is limited because patients become refractory to calcitonin after several days (the calcitonin "escap...

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Détails bibliographiques
Publié dans:J Clin Invest
Auteurs principaux: Takahashi, S, Goldring, S, Katz, M, Hilsenbeck, S, Williams, R, Roodman, G D
Format: Artigo
Langue:Inglês
Publié: American Society for Clinical Investigation 1995
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295397/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7814611/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117634
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