Engineered cell surface expression of membrane immunoglobulin as a means to identify monoclonal antibody-secreting hybridomas

Monoclonal antibodies (mAbs) have proven to be effective biological reagents in the form of therapeutic drugs and diagnostics for many pathologies, as well as valuable research tools. Existing methods for isolating mAb-producing hybridomas are tedious and time consuming. Herein we describe a novel s...

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Bibliographische Detailangaben
Hauptverfasser: Price, Paul W., McKinney, Elizabeth C., Wang, Youliang, Sasser, Loren E., Kandasamy, Muthugapatti K., Matsuuchi, Linda, Milcarek, Christine, Deal, Roger B., Culver, Deborah G., Meagher, Richard B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953942/
https://ncbi.nlm.nih.gov/pubmed/19187782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2009.01.005
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