Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation

Ldb1 and erythroid partners SCL, GATA-1, and LMO2 form a complex that is required to establish spatial proximity between the β-globin locus control region and gene and for transcription activation during erythroid differentiation. Here we show that Ldb1 controls gene expression at multiple levels. L...

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Hlavní autoři: Song, Sang-Hyun, Kim, AeRi, Ragoczy, Tobias, Bender, M. A., Groudine, Mark, Dean, Ann
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2010
Témata:
Red Cells, Iron, and Erythropoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953839/
https://ncbi.nlm.nih.gov/pubmed/20570862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-272252
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