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Multiple functions of Ldb1 required for β-globin activation during erythroid differentiation
Ldb1 and erythroid partners SCL, GATA-1, and LMO2 form a complex that is required to establish spatial proximity between the β-globin locus control region and gene and for transcription activation during erythroid differentiation. Here we show that Ldb1 controls gene expression at multiple levels. L...
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| Autores principales: | , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953839/ https://ncbi.nlm.nih.gov/pubmed/20570862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-03-272252 |
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