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Regulation of a Phage Endolysin by Disulfide Caging

In contrast to canonical phage endolysins, which require holin-mediated disruption of the membrane to gain access to attack the cell wall, signal anchor release (SAR) endolysins are secreted by the host sec system, where they accumulate in an inactive form tethered to the membrane by their N-termina...

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Autori principali: Kuty, Gabriel F., Xu, Min, Struck, Douglas K., Summer, Elizabeth J., Young, Ry
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953681/
https://ncbi.nlm.nih.gov/pubmed/20833810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00674-10
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