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Residue Histidine 669 Is Essential for the Catalytic Activity of Bacillus anthracis Lethal Factor
The lethal factor (LF) of Bacillus anthracis is a Zn(2+)-dependent metalloprotease which plays an important role in anthrax virulence. This study was aimed at identifying the histidine residues that are essential to the catalytic activities of LF. The site-directed mutagenesis was employed to replac...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2953669/ https://ncbi.nlm.nih.gov/pubmed/20833809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00485-10 |
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