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Human anti-phosphorylcholine antibodies share idiotopes and are self-binding.

We have previously shown that BALB/c antipneumococcal polysaccharide antibodies with phosphorylcholine (PC) specificity are self-binding, mediated by hypervariable sequence structure of the heavy chain. We extended the observation of self-binding anti-PC antibodies to naturally occurring human anti-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Halpern, R, Kaveri, S V, Köhler, H
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1991
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295366/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115328
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