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Pro-Inflammatory Cytokine Surge After Injury Stimulates An Airway Immunoglobulin A Increase

BACKGROUND: Injury stimulates an innate airway IgA response in severely injured patients, which also occurs in mice. Tumor necrosis factor-alpha (TNF-α) and interleukin-1 beta (IL-1β) stimulate the production of polymeric immunoglobulin receptor (pIgR), the protein required to transport immunoglobul...

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Bibliographische Detailangaben
Hauptverfasser: Jonker, Mark A, Sano, Yoshifumi, Hermsen, Joshua L, Lan, Jinggang, Kudsk, Kenneth A
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953611/
https://ncbi.nlm.nih.gov/pubmed/20173656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/TA.0b013e3181c45284
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