Prostacyclin production and mediation of adenylate cyclase activity in the pulmonary artery. Alterations after prolonged hypoxia in the rat.

Prostacyclin is a critical mediator of structure and function in the pulmonary circulation, causing both the inhibition of vascular smooth muscle growth and vasodilation via the stimulation of adenylate cyclase. To examine the potential role of alterations in prostacyclin production or mechanism of...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Shaul, P W, Kinane, B, Farrar, M A, Buja, L M, Magness, R R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1991
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1864958/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115324
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