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Effector mechanisms in organ-specific autoimmunity. I. Characterization of a CD8+ T cell line that mediates murine interstitial nephritis.

To further investigate mechanisms of cell-mediated tissue destruction in an organ-specific autoimmune disease, we have established and characterized a nephritogenic CD8+ T cell line. This target antigen-specific effector T cell line, M52, was derived from bulk populations of CD8+ T cells isolated fr...

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Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Meyers, C M, Kelly, C J
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1907613/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115319
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