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Kinesin-1 and dynein at the nuclear envelope mediate the bidirectional migrations of nuclei

Kinesin-1 and dynein are recruited to the nuclear envelope by the Caenorhabditis elegans klarsicht/ANC-1/Syne homology (KASH) protein UNC-83 to move nuclei. The mechanisms of how these motors are coordinated to mediate nuclear migration are unknown. Time-lapse differential interference contrast and...

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Main Authors: Fridolfsson, Heidi N., Starr, Daniel A.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953438/
https://ncbi.nlm.nih.gov/pubmed/20921138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004118
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