The differential interaction of snRNPs with pre-mRNA reveals splicing kinetics in living cells

Precursor messenger RNA (pre-mRNA) splicing is catalyzed by the spliceosome, a large ribonucleoprotein (RNP) complex composed of five small nuclear RNP particles (snRNPs) and additional proteins. Using live cell imaging of GFP-tagged snRNP components expressed at endogenous levels, we examined how t...

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Detalhes bibliográficos
Main Authors: Huranová, Martina, Ivani, Ivan, Benda, Aleš, Poser, Ina, Brody, Yehuda, Hof, Martin, Shav-Tal, Yaron, Neugebauer, Karla M., Staněk, David
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953428/
https://ncbi.nlm.nih.gov/pubmed/20921136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201004030
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