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Redirection of Silencing Targets by Adenosine-to-Inosine Editing of miRNAs

Primary transcripts of certain microRNA (miRNA) genes are subject to RNA editing that converts adenosine to inosine. However, the importance of miRNA editing remains largely undetermined. Here we report that tissue-specific adenosine-to-inosine editing of miR-376 cluster transcripts leads to predomi...

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Main Authors: Kawahara, Yukio, Zinshteyn, Boris, Sethupathy, Praveen, Iizasa, Hisashi, Hatzigeorgiou, Artemis G., Nishikura, Kazuko
格式: Artigo
語言:Inglês
出版: 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953418/
https://ncbi.nlm.nih.gov/pubmed/17322061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1138050
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