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Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol.

Clearance of excess cholesterol from cells by HDL is facilitated by the interaction of HDL apolipoproteins with cell-surface binding sites or receptors, a process that may be important in preventing atherosclerosis. In this study, synthetic peptides containing 18-mer amphipathic helices of the class...

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Published in:J Clin Invest
Main Authors: Mendez, A J, Anantharamaiah, G M, Segrest, J P, Oram, J F
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295333/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7929849/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117515
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