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Amino acid substitutions in the hormone-binding domain of the human androgen receptor alter the stability of the hormone receptor complex.

We have investigated the basis of androgen resistance in seven unrelated individuals with complete testicular feminization or Reifenstein syndrome caused by single amino acid substitutions in the hormone-binding domain of the androgen receptor. Monolayer-binding assays of cultured genital skin fibro...

詳細記述

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書誌詳細
主要な著者: Marcelli, M, Zoppi, S, Wilson, C M, Griffin, J E, McPhaul, M J
フォーマット: Artigo
言語:Inglês
出版事項: 1994
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC295325/
https://ncbi.nlm.nih.gov/pubmed/7929841
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