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Mutation Analysis of the PVRL1 Gene in Caucasians with Nonsyndromic Cleft Lip/Palate

Nonsyndromic cleft lip with or without cleft palate (nsCL/P, MIM 119530) is perhaps the most common major birth defect. Homozygous PVRL1 loss-of-function mutations result in an autosomal recessive CL/P syndrome, CLPED1, and a PVRL1 nonsense mutation is associated with sporadic nsCL/P in Northern Ven...

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Autori principali: Sözen, Mehmet A., Hecht, Jacqueline T., Spritz, Richard A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953240/
https://ncbi.nlm.nih.gov/pubmed/19715471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2009.0052
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