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Ultrastructural and Biophysical Characterization of Hepatitis C Virus Particles Produced in Cell Culture

We analyzed the biochemical and ultrastructural properties of hepatitis C virus (HCV) particles produced in cell culture. Negative-stain electron microscopy revealed that the particles were spherical (∼40- to 75-nm diameter) and pleomorphic and that some of them contain HCV E2 protein and apolipopro...

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Detalhes bibliográficos
Main Authors: Gastaminza, Pablo, Dryden, Kelly A., Boyd, Bryan, Wood, Malcolm R., Law, Mansun, Yeager, Mark, Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953183/
https://ncbi.nlm.nih.gov/pubmed/20686033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00526-10
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