An RNA Pseudoknot Is Required for Production of Yellow Fever Virus Subgenomic RNA by the Host Nuclease XRN1

Cells and mice infected with arthropod-borne flaviviruses produce a small subgenomic RNA that is colinear with the distal part of the viral 3′-untranslated region (UTR). This small subgenomic flavivirus RNA (sfRNA) results from the incomplete degradation of the viral genome by the host 5′-3′ exonucl...

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Autors principals: Silva, Patrícia A. G. C., Pereira, Carina F., Dalebout, Tim J., Spaan, Willy J. M., Bredenbeek, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Genome Replication and Regulation of Viral Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953177/
https://ncbi.nlm.nih.gov/pubmed/20739539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01047-10
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