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Culturing the Unculturable: Human Coronavirus HKU1 Infects, Replicates, and Produces Progeny Virions in Human Ciliated Airway Epithelial Cell Cultures

Culturing newly identified human lung pathogens from clinical sample isolates can represent a daunting task, with problems ranging from low levels of pathogens to the presence of growth suppressive factors in the specimens, compounded by the lack of a suitable tissue culture system. However, it is c...

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Main Authors: Pyrc, Krzysztof, Sims, Amy C., Dijkman, Ronald, Jebbink, Maarten, Long, Casey, Deming, Damon, Donaldson, Eric, Vabret, Astrid, Baric, Ralph, van der Hoek, Lia, Pickles, Raymond
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953148/
https://ncbi.nlm.nih.gov/pubmed/20719951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00947-10
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