Native and recombinant human hepatocyte growth factors are highly potent promoters of DNA synthesis in both human and rat hepatocytes.

Human hepatocyte growth factor (hHGF) has recently been expressed as a recombinant polypeptide from Chinese hampster ovary cell transfectants. Using a primary rat hepatocyte bioassay, we have tested the biological activity of recombinant hHGF and compared it with native hHGF. Dose-response curves we...

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Publicado en:J Clin Invest
Autores principales: Strain, A J, Ismail, T, Tsubouchi, H, Arakaki, N, Hishida, T, Kitamura, N, Daikuhara, Y, McMaster, P
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295309/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1827130/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115207
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