Use of Acyclovir for Suppression of Human Immunodeficiency Virus Infection Is Not Associated with Genotypic Evidence of Herpes Simplex Virus Type 2 Resistance to Acyclovir: Analysis of Specimens from Three Phase III Trials

Herpes simplex virus type 2 (HSV-2) is the most common cause of genital ulcer disease and is a cofactor for HIV-1 acquisition and transmission. We analyzed specimens from three separate phase III trials of acyclovir (ACV) for prevention of HIV-1 acquisition and transmission to determine if failure o...

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Bibliographic Details
Main Authors: Watson-Jones, Deborah, Wald, Anna, Celum, Connie, Lingappa, Jairam, Weiss, Helen A., Changalucha, John, Baisley, Kathy, Tanton, Clare, Hayes, Richard J., Marshak, Joshua O., Gladden, Rula Green, Koelle, David M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Virology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953087/
https://ncbi.nlm.nih.gov/pubmed/20702659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.01263-10
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