Engineered Lactic Acid Bacterium Lactococcus lactis Capable of Binding Antibodies and Tumor Necrosis Factor Alpha

We have optimized the display of the B domain of staphylococcal protein A on the surface of Lactococcus lactis. The maximum binding capacity was estimated at 0.146 μg of antibody per 10(8) cells and was sustained at 86% after treatment with simulated gastric juice. A tumor necrosis factor alpha (TNF...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ravnikar, Matjaž, Štrukelj, Borut, Obermajer, Nataša, Lunder, Mojca, Berlec, Aleš
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology (ASM) 2010
Pynciau:
Biotechnology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953040/
https://ncbi.nlm.nih.gov/pubmed/20802083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00190-10
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