Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.

Insulin resistance is an important metabolic abnormality often associated with infections, cancer, obesity, and especially non-insulin-dependent diabetes mellitus (NIDDM). We have previously demonstrated that tumor necrosis factor-alpha produced by adipose tissue is a key mediator of insulin resista...

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Sonraí Bibleagrafaíochta
Main Authors: Hotamisligil, G S, Budavari, A, Murray, D, Spiegelman, B M
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1994
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC295304/
https://ncbi.nlm.nih.gov/pubmed/7523453
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