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Landscape Phage Fusion Protein-mediated Targeting of Nanomedicines Enhances their Prostate Tumor Cell Association and Cytotoxic Efficiency

Tumor-specific cytotoxicity of drugs can be enhanced by targeting them to tumor receptors using tumor-specific ligands. Phage display offers a high-throughput approach to screen for the targeting ligands. We have successfully isolated phage fusion peptides selective and specific for PC3 prostate can...

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Detalhes bibliográficos
Main Authors: Jayanna, P.K., Bedi, D, Gillespie, J.W., DeInnocentes, P., Wang, T, Torchilin, V.P, Bird, R.C., Petrenko, V.A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952829/
https://ncbi.nlm.nih.gov/pubmed/20138246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2010.01.005
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