Phenotypic correction of Fanconi anemia in human hematopoietic cells with a recombinant adeno-associated virus vector.

Fanconi anemia (FA) is a recessive inherited disease characterized by defective DNA repair. FA cells are hypersensitive to DNA cross-linking agents that cause chromosomal instability and cell death. FA is manifested clinically by progressive pancytopenia, variable physical anomalies, and predisposit...

Full description

Saved in:
Bibliographic Details
Main Authors: Walsh, C E, Nienhuis, A W, Samulski, R J, Brown, M G, Miller, J L, Young, N S, Liu, J M
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC295276/
https://ncbi.nlm.nih.gov/pubmed/7929819
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items