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In vivo transfer of nitric oxide between a plasma protein-bound reservoir and low molecular weight thiols.

Plasma albumin reacts with nitric oxide (NO) to form the bioactive adduct, S-nitroso-albumin (S-NO-albumin). The limited intracellular access of S-NO-albumin suggests the need for a vascular transfer mechanism of NO from a large plasma S-NO-albumin pool to effect biologic function. To study the role...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Principais autores: Scharfstein, J S, Keaney, J F, Slivka, A, Welch, G N, Vita, J A, Stamler, J S, Loscalzo, J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 1994
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7929818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117480
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