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Can Self-Inhibitory Peptides be Derived from the Interfaces of Globular Protein-Protein Interactions?
In this study, we assess on a large scale the possibility of deriving self-inhibitory peptides from protein domains with globular architectures. Such inhibitory peptides would inhibit interactions of their origin domain by mimicking its mode of binding to cognate partners, and could serve as promisi...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952690/ https://ncbi.nlm.nih.gov/pubmed/20607702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22785 |
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