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Can Self-Inhibitory Peptides be Derived from the Interfaces of Globular Protein-Protein Interactions?

In this study, we assess on a large scale the possibility of deriving self-inhibitory peptides from protein domains with globular architectures. Such inhibitory peptides would inhibit interactions of their origin domain by mimicking its mode of binding to cognate partners, and could serve as promisi...

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Bibliografische gegevens
Hoofdauteurs: London, Nir, Raveh, Barak, Movshovitz-Attias, Dana, Schueler-Furman, Ora
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952690/
https://ncbi.nlm.nih.gov/pubmed/20607702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22785
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