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The pentraxins, C-reactive protein and serum amyloid P component, are cleared and catabolized by hepatocytes in vivo.

The cellular sites of clearance and degradation of the pentraxin plasma proteins, C-reactive protein, the classical acute phase reactant, and serum amyloid P component (SAP), a universal constituent of amyloid deposits, were sought using the ligand 125I-tyramine cellobiose (TC) which is substantiall...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Hutchinson, W L, Noble, G E, Hawkins, P N, Pepys, M B
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295264/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7929814/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117474
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