Temperature-dependent modulation of lipopolysaccharide-induced interleukin-1 beta and tumor necrosis factor alpha expression in cultured human astroglial cells by dexamethasone and indomethacin.

In bacterial meningitis, LPS induces production in cerebrospinal fluid of the cytokines IL-1 beta and tumor necrosis factor alpha (TNF alpha), which are the principle mediators of meningeal inflammation. IL-1 beta and TNF alpha induce fever, and elevated temperature may affect cytokine expression. D...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Velasco, S, Tarlow, M, Olsen, K, Shay, J W, McCracken, G H, Nisen, P D
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295263/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2022738/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115184
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