Characterizing DNA Condensation and Conformational Changes in Organic Solvents

Organic solvents offer a new approach to formulate DNA into novel structures suitable for gene delivery. In this study, we examined the in situ behavior of DNA in N, N-dimethylformamide (DMF) at low concentration via laser light scattering (LLS), TEM, UV absorbance and Zeta potential analysis. Resul...

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Main Authors: Ke, Fuyou, Luu, Yen Kim, Hadjiargyrou, Michael, Liang, Dehai
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952604/
https://ncbi.nlm.nih.gov/pubmed/20949017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013308
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