Differential Genetic Regulation of Canine Hip Dysplasia and Osteoarthritis

BACKGROUND: Canine hip dysplasia (HD) is a common polygenic trait characterized by hip malformation that results in osteoarthritis (OA). The condition in dogs is very similar to developmental dysplasia of the human hip which also leads to OA. METHODOLOGY/PRINCIPAL FINDINGS: A total of 721 dogs, incl...

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Hauptverfasser: Zhou, Zhengkui, Sheng, Xihui, Zhang, Zhiwu, Zhao, Keyan, Zhu, Lan, Guo, Gang, Friedenberg, Steve G., Hunter, Linda S., Vandenberg-Foels, Wendy S., Hornbuckle, William E., Krotscheck, Ursula, Corey, Elizabeth, Moise, Nancy S., Dykes, Nathan L., Li, Junya, Xu, Shangzhong, Du, Lixin, Wang, Yachun, Sandler, Jody, Acland, Gregory M., Lust, George, Todhunter, Rory J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952589/
https://ncbi.nlm.nih.gov/pubmed/20949002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013219
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