Apolipoprotein B genetic variants modify the response to fenofibrate: a GOLDN study

Hypertriglyceridemia, defined as a triglyceride measurement > 150 mg/dl, occurs in up to 34% of adults. Fenofibrate is a commonly used drug to treat hypertriglyceridemia, but response to fenofibrate varies considerably among individuals. We sought to determine if genetic variation in apolipoprote...

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Autori principali: Wojczynski, Mary K., Gao, Guimin, Borecki, Ingrid, Hopkins, Paul N., Parnell, Laurence, Lai, Chao-Qiang, Ordovas, Jose M., Chung, B. Hong, Arnett, Donna K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Patient-Oriented and Epidemiological Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952572/
https://ncbi.nlm.nih.gov/pubmed/20724655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P001834
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