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Interleukin 12 exerts a differential effect on the maturation of neonatal and adult human CD45R0- CD4 T cells.

It is now recognized that IL-12 plays a predominant role in protective immunity against intracellular pathogens by promoting the development of T helper type 1 (Th1) responses. We here report the unexpected observations that IL-12 exerts differential effects on the maturation of "native" h...

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Autors principals: Shu, U, Demeure, C E, Byun, D G, Podlaski, F, Stern, A S, Delespesse, G
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295253/
https://ncbi.nlm.nih.gov/pubmed/7929809
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