Anterior Visceral Endoderm SMAD4 Signaling Specifies Anterior Embryonic Patterning and Head Induction in Mice

SMAD4 serves as a common mediator for signaling of TGF-β superfamily. Previous studies illustrated that SMAD4-null mice die at embryonic day 6.5 (E6.5) due to failure of mesoderm induction and extraembryonic defects; however, functions of SMAD4 in each germ layer remain elusive. To investigate this,...

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Bibliografske podrobnosti
Main Authors: Li, Cuiling, Li, Yi-Ping, Fu, Xin-Yuan, Deng, Chu-Xia
Format: Artigo
Jezik:Inglês
Izdano: Ivyspring International Publisher 2010
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952407/
https://ncbi.nlm.nih.gov/pubmed/20941375
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