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Adenosine diphosphate-ribosylation of G-actin by botulinum C2 toxin increases endothelial permeability in vitro.

The endothelial cytoskeleton is believed to play an important role in the regulation of endothelial permeability. We used botulinum C2 toxin to perturb cellular actin and determined its effect on the permeability of endothelial cell monolayers derived from porcine pulmonary arteries. The substrate f...

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Autors principals: Suttorp, N, Polley, M, Seybold, J, Schnittler, H, Seeger, W, Grimminger, F, Aktories, K
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC295240/
https://ncbi.nlm.nih.gov/pubmed/2022729
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