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Generation and analysis of clonal IgM- and IgG-producing human B cell lines expressing an anti-DNA-associated idiotype.

This study describes a methodology for generating stable, cloned, EBV-transformed IgG- and IgM-producing human B cell lines. Using these lines we have characterized immunoglobulin V gene utilization in an anti-DNA-associated idiotypic system. The 31 anti-DNA-associated idiotype is encoded preferenti...

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Udgivet i:J Clin Invest
Principais autores: Manheimer-Lory, A J, Davidson, A, Watkins, D, Hannigan, N R, Diamond, B A
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1991
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295231/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1708781/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115162
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