Francisella Acid Phosphatases Inactivate the NADPH Oxidase in Human Phagocytes

Francisella tularensis contains four putative acid phosphatases that are conserved in Francisella novicida. An F. novicida quadruple mutant (AcpA, AcpB, AcpC, and Hap [ΔABCH]) is unable to escape the phagosome or survive in macrophages and is attenuated in the mouse model. We explored whether reduce...

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Main Authors: Mohapatra, Nrusingh P., Soni, Shilpa, Rajaram, Murugesan V. S., Dang, Pham My-Chan, Reilly, Tom J., El-Benna, Jamel, Clay, Corey D., Schlesinger, Larry S., Gunn, John S.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952287/
https://ncbi.nlm.nih.gov/pubmed/20348422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903413
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