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Dependence on Vitamin K-dependent Protein S for Eukaryotic Cell Secretion of the β-Chain of C4b-binding Protein

The anticoagulant vitamin K-dependent protein S (PS) circulates in plasma in two forms, 30% free and 70% being bound to the complement regulatory protein C4b-binding protein (C4BP). The major C4BP isoform consists of 7 α-chains and 1 β-chain (C4BPβ(+)), the chains being linked by disulfide bridges....

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Detalhes bibliográficos
Main Authors: Carlsson, Sofia, Dahlbäck, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952205/
https://ncbi.nlm.nih.gov/pubmed/20693287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.148452
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