Endotoxin and cytokines increase hepatic messenger RNA levels and serum concentrations of apolipoprotein J (clusterin) in Syrian hamsters.

Infection and inflammation induce alterations in hepatic synthesis and plasma concentrations of the acute phase proteins. Our results show that apolipoprotein (apo) J is a positive acute phase protein. Endotoxin (LPS), tumor necrosis factor (TNF), and interleukin (IL)-1 increased hepatic mRNA and se...

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Pubblicato in:	J Clin Invest
Autori principali:	Hardardóttir, I, Kunitake, S T, Moser, A H, Doerrler, W T, Rapp, J H, Grünfeld, C, Feingold, K R
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295216/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8083372/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117449
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