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Potential redox-sensitive Akt activation by dopamine activates Bad and promotes cell death in melanocytes

Dopamine (DA) is a well known oxidative neurotoxin. In addition, Akt has been reported to deliver a survival signal that inhibits apoptosis. However, it has also been reported that chronic Akt activation leads to apoptosis in response to oxidative stress. The objective of the present study was to in...

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Detaylı Bibliyografya
Asıl Yazarlar: Choi, Hye-Ryung, Shin, Jung-Won, Lee, Hyun-Kyoung, Kim, Jin-Young, Huh, Chang-Hun, Youn, Sang-Woong, Park, Kyoung Chan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952081/
https://ncbi.nlm.nih.gov/pubmed/20716947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/oxim.3.3.8
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