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Potential redox-sensitive Akt activation by dopamine activates Bad and promotes cell death in melanocytes

Dopamine (DA) is a well known oxidative neurotoxin. In addition, Akt has been reported to deliver a survival signal that inhibits apoptosis. However, it has also been reported that chronic Akt activation leads to apoptosis in response to oxidative stress. The objective of the present study was to in...

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Autors principals: Choi, Hye-Ryung, Shin, Jung-Won, Lee, Hyun-Kyoung, Kim, Jin-Young, Huh, Chang-Hun, Youn, Sang-Woong, Park, Kyoung Chan
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952081/
https://ncbi.nlm.nih.gov/pubmed/20716947
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/oxim.3.3.8
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