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Carbamazepine but not valproate induces CYP2A6 activity in smokers with mental illness

BACKGROUND: Anti-epileptic drugs (AED) are increasingly used in the management of serious mental illness yet their effects on nicotine metabolism have not been studied. METHODS: This study investigated the effects of 3 AED (carbamazepine, CBZ; oxcarbazepine, OCB or valproic acid, VPA) on nicotine an...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Williams, Jill M, Gandhi, Kunal K, Benowitz, Neal L
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952059/
https://ncbi.nlm.nih.gov/pubmed/20719908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0384
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