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In vitro model of intestinal crypt abscess. A novel neutrophil-derived secretagogue activity.

In order to model crypt abscesses, a histological finding which correlates with disease activity in intestinal inflammation, human polymorphonuclear leukocytes (PMN) were layered onto monolayers of the human intestinal epithelial cell line T84, a crypt-like epithelium which is capable of Cl- secreti...

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Published in:J Clin Invest
Main Authors: Nash, S, Parkos, C, Nusrat, A, Delp, C, Madara, J L
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1991
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Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC295203/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2010557/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115156
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