Let-7 MicroRNA Family Is Selectively Secreted into the Extracellular Environment via Exosomes in a Metastatic Gastric Cancer Cell Line

BACKGROUND: Exosomes play a major role in cell-to-cell communication, targeting cells to transfer exosomal molecules including proteins, mRNAs, and microRNAs (miRNAs) by an endocytosis-like pathway. miRNAs are small noncoding RNA molecules on average 22 nucleotides in length that regulate numerous b...

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Bibliografiske detaljer
Main Authors: Ohshima, Keiichi, Inoue, Kanako, Fujiwara, Akemi, Hatakeyama, Keiichi, Kanto, Kaori, Watanabe, Yuko, Muramatsu, Koji, Fukuda, Yorikane, Ogura, Shun-ichiro, Yamaguchi, Ken, Mochizuki, Tohru
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951912/
https://ncbi.nlm.nih.gov/pubmed/20949044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013247
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