(1)H-NMR-Based Metabolomic Profiling of CSF in Early Amyotrophic Lateral Sclerosis

BACKGROUND: Pathophysiological mechanisms involved in amyotrophic lateral sclerosis (ALS) are complex and none has identified reliable markers useful in routine patient evaluation. The aim of this study was to analyze the CSF of patients with ALS by (1)H NMR (Nuclear Magnetic Resonance) spectroscopy...

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Main Authors: Blasco, Hélène, Corcia, Philippe, Moreau, Caroline, Veau, Ségolène, Fournier, Clémentine, Vourc'h, Patrick, Emond, Patrick, Gordon, Paul, Pradat, Pierre-François, Praline, Julien, Devos, David, Nadal-Desbarats, Lydie, Andres, Christian R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951909/
https://ncbi.nlm.nih.gov/pubmed/20949041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013223
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