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Molecular basis of androgen resistance in a family with a qualitative abnormality of the androgen receptor and responsive to high-dose androgen therapy.

We have examined the nature of the mutant androgen receptor in a family with a severe defect in virilization associated with a qualitative defect in receptor function. The androgen receptor gene in this family contains two structural alterations: a single nucleotide substitution at position 2444 in...

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Main Authors: McPhaul, M J, Marcelli, M, Tilley, W D, Griffin, J E, Isidro-Gutierrez, R F, Wilson, J D
格式: Artigo
語言:Inglês
出版: 1991
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC295186/
https://ncbi.nlm.nih.gov/pubmed/2010552
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