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Lymphotoxin-alpha contributes to lymphangiogenesis

Lymphotoxin-α (LTα), lymphotoxin-β (LTβ), and tumor necrosis factor-α (TNFα) are inflammatory mediators that play crucial roles in lymphoid organ development. We demonstrate here that LTα also contributes to the function of lymphatic vessels and to lymphangiogenesis during inflammation. LTα(−/−) mic...

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Detalhes bibliográficos
Main Authors: Mounzer, Rawad H., Svendsen, Oyvind S., Baluk, Peter, Bergman, Cheryl M., Padera, Timothy P., Wiig, Helge, Jain, Rakesh K., McDonald, Donald M., Ruddle, Nancy H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951858/
https://ncbi.nlm.nih.gov/pubmed/20566898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-12-256065
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