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Arrhythmia in Heart and Brain: KCNQ1 Mutations Link Epilepsy and Sudden Unexplained Death
Sudden unexplained death in epilepsy (SUDEP) is a catastrophic complication of human idiopathic epilepsy, with an estimated prevalence of up to 18%. A molecular mechanism and an identified therapy have remained elusive. Here we find that epilepsy occurs in mouse lines bearing dominant human LQT1 mut...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2951754/ https://ncbi.nlm.nih.gov/pubmed/20368164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3000289 |
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