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LCK, survivin and PI-3K in the molecular biomarker profiling of oral lichen planus and oral squamous cell carcinoma

T cell signaling is critical in oral lichen planus (OLP) based on the pathogenesis of this chronic inflammatory autoimmune mucocutaneous lesion. Lck plays a key role in T cell signaling; ultimately this signaling affects other targets such as PI-3K. Excessive activity in PI-3K inhibits apoptosis and...

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Detalhes bibliográficos
Principais autores: Oluwadara, Oluwadayo, Giacomelli, Luca, Christensen, Russell, Kossan, George, Avezova, Raisa, Chiappelli, Francesco
Formato: Artigo
Idioma:Inglês
Publicado em: Biomedical Informatics Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951717/
https://ncbi.nlm.nih.gov/pubmed/20975919
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